A question for Lead Connectome

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  • 02/08/2019 at 3:41 PM #6593
    dargonchow1
    Participant

    Dear developer

    My research interest in focusing on using functional connectome as the surrogate marker in disease investigation. After using Lead Connectome, I think the default option is perform WM, CSF and global signal regression in functional connectome estimation. However, I wish to construct the functional connectome without global signal regression. Could you tell me how to disable the option of global signal regression in Lead Connectome.

    Thank you

    02/08/2019 at 4:32 PM #6594
    andreashorn
    Keymaster

    Hi there,

    no, by default, the global signal is not regressed out (but it’s calculated).
    https://github.com/leaddbs/leaddbs/blob/master/connectomics/ea_extract_timecourses.m#L193

    As you can see, the according line is commented out – if instead you’d want to correct for the global signal, you could uncomment that line ^^.

    Best, Andy

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