this used to work in the past but in the novel versions, Lead-DBS performs reconstructions hybridly within patient and MNI space. Thus, a file that warps from subject to MNI space is needed. However, it doesn’t need to be an SPM file, ANTs is also supported. With which software did you normalize your data? Maybe the deformation file mapping from subject to MNI is similarly structured than y_ files or ANTs normalization parameters and we can figure out a workaround for you?